A common saying among pet owners is that the hardest thing about loving a dog is saying goodbye. Having a senior dog, especially one raised from a puppy, can be difficult not just because of the inevitable, but also because the pet may be going through age-related ailments or disease before crossing over. It’s a hard thing to experience anyway, but especially when you remember how they were in their prime. Well, veterinary scientists are testing a daily pill that extends a dog’s lifespan while also maintaining their quality of life.
Loyal, a biotech company based in San Francisco, has been trying to develop anti-aging drugs for dogs ever since it was founded. After years of research and testing, they have developed LOY-002, a beef-flavored daily prescription pill for senior dogs aged 10 and older that weigh over 14 pounds. Early testing shows that the pill can add years to a dog’s life, especially larger breeds.
What does this dog lifespan pill do?
The pill interacts and manipulates IGF-1 (Insulin-Like Growth Factor 1), a hormone that’s key to a dog’s cellular growth and metabolism. IGF-1 helps a dog grow in both size and calorie consumption. This hormone helps make young puppies become strong adult dogs. However, it also continues and accelerates aging at a cellular level when a dog is fully grown.
This explains why many larger breeds of dogs tend to live shorter lives than smaller ones. Their IGF-1 levels are higher. It moves them faster towards age-related diseases and discomfort than smaller dogs.
By reducing the excessive IGF-1, LOY-002 reduces the speed of a larger dog’s biological clock. It doesn’t just make them “feel” younger. Slowing everything down adds years to their life and curbs the risk of age-related organ dysfunction, disease, and early death. After thorough testing, LOY-002 cleared two out of the three sections of acceptance before being fully vetted by the Food and Drug Administration.
“Since founding Loyal six years ago, my goal has always been to get the first drug FDA approved for lifespan extension. This safety acceptance brings us very close to achieving that vision,” said Loyal Founder and CEO Celine Halioua. “We are well on our way to bringing the first dog longevity drugs to market.”
How can a senior dog live longer?
Should Loyal receive that final approval, the LOY-002 drug should go to market before the end of 2026. However, veterinarians and dog care experts have some tips on how to help your older dog live longer and healthier.
Visit your dog’s veterinarian often for checkups and keep them notified of any changes in their behavior. They may recommend a specific diet for your dog at their advanced age. Similar to humans, older dogs are encouraged to follow a healthy diet. They should exercise regularly (through walks or playtime) to keep a healthy weight and keep joints strong.
If your dog has joint trouble, your vet may recommend some supplements to help the dog’s mobility and comfort. No matter the issue, it is best to consult with a veterinarian before making lifestyle changes for your dog.
Such advice can help both you and your dog live full lives together. It may also add a few more years of furry companionship along the way, too.
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